![]() Uniform Distribution – this ignores the usage of each codon and randomly assigns an appropriate codon for each amino acid.Again, you will get a different sequence each time you invoke this. bias organism this should, in theory, give you the best chance of high expression. But as the overall codon usage in the DNA sequence is guaranteed to be as close as possible to the codon usage in the. Again, each time you invoke the algorithm, it will produce a different sequence. ![]() However, this version tries to ensure that the final DNA sequence has a codon usage profile as closely matching as possible to the codon usage of the selected. Similar to the Frequency Distribution, this chooses a random codon, biased towards the most frequently used codons for each amino acid.
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